The Dual Innervation of the Gluteus Maximus Associated with Other Anatomical Variations of the Gluteal Region
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Case Report
P: 136-139
June 2024

The Dual Innervation of the Gluteus Maximus Associated with Other Anatomical Variations of the Gluteal Region

Medeni Med J 2024;39(2):136-139
1. All India Institute of Medical Sciences Bibinagar, Department of Anatomy, Hyderabad, India
No information available.
No information available
Received Date: 09.01.2024
Accepted Date: 28.04.2024
Online Date: 28.06.2024
Publish Date: 28.06.2024
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ABSTRACT

The gluteus maximus (GM) is a big quadrilateral musculature that lines the rear portion of the pelvis. It is innervated by the inferior gluteal nerve. The sciatic nerve, inferior gluteal nerve, and posterior cutaneous nerve of the thigh are branches of the sacral plexus. The superior and inferior gluteal arteries are the chief arterial supply to the gluteal region. In the present case, there was a dual innervation of the GM. The superior gluteal artery and the superior gluteal nerve was piercing the piriformis and the inferior gluteal artery was running between the posterior cutaneous nerve of the thigh and the inferior gluteal nerve. According to our literature review, anatomical studies in which this cadaveric procedure has been performed have not been previously reported. The anatomical variations of the gluteal region are important to surgeons, physicians, anatomists, and nurses.

Keywords:
Gluteus maximus, sciatic nerve, cadaver, dual innervation, piriformis

INTRODUCTION

The gluteus maximus (GM) is a big quadrilateral musculature that lines the rear portion of the pelvis. It originates from the iliac crest, posterior part of the gluteal surface of the ilium, dorsal part of the sacrum, side of the coccyx, and sacrotuberous ligament. Three-quarters of it is placed into the iliotibial tract, while the other quarter is introduced into the gluteal tuberosity. It is supplied by the inferior gluteal nerve (IGN). GM is a chief extensor of the hip joint and acts as an anti-gravity muscle1.

The sacral plexus (SP) branch known as the IGN has root values of L5, S1, and S2. The sciatic nerve (SN) is the thickest in the body and is a branch of the SP with root values L4-S3. Another branch of SP with root values of S1-S3 is the posterior cutaneous nerve of the thigh (PCNT). The inferior gluteal artery (IGA) supplies blood to the GM after entering the gluteal region through the greater sciatic foramen. It is a branch from the internal iliac artery’s anterior segment. The superior gluteal artery (SGA) is a branch of the posterior segment of the internal iliac artery that reaches the gluteal region via the greater sciatic foramen and passes above the piriformis, accompanied by the superior gluteal nerve1.

In this case report, we present a unique rare case of dual innervation of the GM and IGA compression. SGA and SGN were piercing the piriformis. Variations in the innervation of GM are exceedingly rare. According to our literature review, anatomical studies in which this cadaveric procedure has been performed have not been previously reported.

CASE REPORT

During the usual dissection of a 61-year-old female corpse, which had been embalmed in formalin during hands-on training for undergraduate and postgraduate medical students at the department of anatomy, a discrepancy was observed in regular cadaveric dissection; therefore, it was exempted from review by the ethics board. As it was a cadaver, the body would come under a body donation program, the consent was given by the next kin of the deceased.

We dissected the GM into two halves and reflected it as superomedial and inferolateral. We found an incidental finding in the right gluteal region; the GM was innervated by the two nerves. The superomedial half of the GM was innervated by the branch of the SN that gave twigs. The inferolateral half of GM was supplied by IGN. The PCNT received an extra branch from the IGN. The IGA ran between the PCNT and the IGN, which led to the compression of the artery, as shown in Figures 1 and 2. SGA and SGN were piercing the piriformis, as shown in Figure 3. The left gluteal region was normal.

DISCUSSION

Quiñones-Rodríquez et al.2 reported bilateral dual innervation of GM by the SN and IGN branches. Those with an aberrant branch from the SN to the GM may be more vulnerable to iatrogenic nerve injury because of intramuscular gluteal injection or surgical procedures2.

Lesser et al.3 described a case in which the components of the SN distal to the piriformis formed a nerve loop. From the nerve loop, some branches innervated the GM, and one branch communicated with the PCNT. These variations increase iatrogenic nerve injuries.

Inflammation of the piriformis muscle is known as piriformis syndrome. Due to inflammation, the SN is compressed, resulting in pain in the inferomedial portion of the gluteal region, sciatica, and dyspareunia in females4. Because of the presence of SN innervation to the GM, the pain may radiate to the entire gluteal region in piriform syndrome cases. In addition, inflammation of the GM strains the aberrant branch of the SN.

Sumalatha et al.5 reported a higher division of the SN into the common peroneal and tibial nerves. The common peroneal nerve enters the gluteal region as two trunks, medial and lateral. GM is innervated by the medial trunk of the common peroneal nerve5. Paval and Nayak6 noticed that IGN is derived from the two roots. One root pierces the piriformis, and the other root emerges from the lower edge of the piriformis6.

Golmohammadi and Delbari7 found a higher division of the SN into the tibial and common peroneal nerves. The IGN originated from the common peroneal nerve7.

The piriformis receives innervation from the anterior rami of S1 and S2. According to Iwanaga et al.8, the innervation of the piriformis was primarily the superior gluteal nerve. In this case, the superior gluteal nerve and SGA were piercing the piriformis.

The PCNT received an extra branch from the IGN. If there is any injury to the IGN, the pain may radiate to the area where the PCNT innervates the region. The most common site for gluteal intramuscular injection was the upper outer quadrant of the GM. In this case, there was dual innervation of the GM by the SN and IGN. The gluteal injections may lead to injury of the SN, and the pain may radiate to the area where it innervates the region.

Tillmann and Verlaufsvarianten des9 explained how the IGN departs the pelvis by piercing the piriformis. Normally, it exits the pelvis distal to the piriformis.

During in utero development, GM originates as two separate parts, the pars-sacroiliaca and pars-coccygea. These two muscle belly fuse in the tenth week of intrauterine life. Usually, these muscles are innervated by one nerve. If the two muscles are innervated by two different nerves, this leads to dual innervation of the GM10.

According to our literature review, anatomical studies in which this cadaveric procedure has been performed have not been previously reported. The most common site for intramuscular injection is the upper outer region of the gluteal region. These variations increase the risk of iatrogenic nerve injuries. Surgeons, physicians, anatomists, and nurses need to understand the distinctions in the gluteal territory.

Acknowledgments: We would like to thank the cadaver’s relatives for giving their relative’s corpse for teaching and research. We would also like to recognize the efforts of anatomy laboratory attendees in maintaining the cadavers and the laboratory regularly.

References

1
Standring S. Gray’s anatomy: the anatomical basis of clinical practice. 41st edition. New York: Elsevier Limited, 2016.
2
Quiñones-Rodríguez J, Camacho-Quiñones A, Cárdenas-Suárez NY, Ramírez N. Dual Innervation to the Gluteus Maximus: A Case Report with Clinical Implications. J Clin of Diagn Res. 2022;16:AD01-3.
3
Lesser ER, Kilgore M, Iwanaga J, et al. A Highly Unusual Source and Course of the Inferior Gluteal Nerve With Related Variations: A Case Report. Cureus. 2023;15:e48694.
4
Kirschner JS, Foye PM, Cole JL. Piriformis syndrome, diagnosis and treatment. Muscle Nerve. 2009;40:10-8.
5
Sumalatha S, D Souza AS, Yadav JS, Mittal SK, Singh A, Kotian SR. An unorthodox innervation of the gluteus maximus muscle and other associated variations: A case report. Australas Med J. 2014;7:419-22.
6
Paval J, Nayak S. A case of bilateral high division of sciatic nerve with a variant inferior gluteal nerve. Neuroanatomy. 2006;5:33-4.
7
Golmohammadi R, Delbari A. Report of a Novel Bilateral Variation of Sciatic and Inferior Gluteal Nerve: A Case Study. Basic Clin Neurosci. 2021;12:421-6.
8
Iwanaga J, Eid S, Simonds E, Schumacher M, Loukas M, Tubbs RS. The majority of piriformis muscles are innervated by the superior gluteal nerve. Clin Anat. 2019;32:282-6.
9
Tillmann B. Verlaufsvarianten des N. gluteus inferior [Variations in the pathway of the inferior gluteal nerve (author’s transl)]. Anat Anz. 1979;145:293-302.
10
Tichý M, Grim M. Morphogenesis of the human gluteus maximus muscle arising from two muscle primordia. Anat Embryol (Berl). 1985;173:275-7.